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Cake day: 2023年6月1日

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  • I suggest read the original study instead of a paper’s interpretation of it. They suggest action, and that’s changing the suggested inhalers people use in most cases. It’s not “blame people for thing”, it’s “here’s a problem and how we can dramatically reduce it with some minor systemic changes”

    All but 2 therapeutic classes (short-acting muscarinic antagonists and ICS-SABAs) had dry powder and/or soft mist inhalers available. If patients during the study period had received the inhalers with the lowest emissions intensity available at the time in each therapeutic class, total emissions would have decreased by 92%, from 24.9 million mtCO2e to 2.1 million mtCO2e (eTable 6 in Supplement 1).

    […]

    This study identifies a high ceiling for potential climate-related gains from switching patients to therapeutically equivalent alternatives. Any such efforts to shift prescribing will likely depend on broadscale formulary changes—and the policies required to incentivize such changes—rather than just individual actions by patients and physicians, who may be limited by payer formularies when choosing particular inhalers

    https://jamanetwork.com/journals/jama/fullarticle/2839471







  • No, it doesn’t tell us nothing. These kinds of limitations are not uncommon for nutrition studies. It just is weaker evidence that doesn’t tell everything we ever might want. Studies will always have some methodological limitations. There is always some factor you might be forgetting or could do better. Science doesn’t work by looking at induvidial studies alone. We take things in aggregate

    That being said, of course things like RCTs will always be preferred and considered much stronger evidence. On that front, there have been some RCTs in other related health risk incidents with similar findings. For instance, I have read about some RCT studies for cardiovascular health. One meat industry funded review of RCT studies on cardiovascular risk for red meat found plant substitution improved predictors of cardiovascular health

    Substituting red meat with high-quality plant protein sources, but not with fish or low-quality carbohydrates, leads to more favorable changes in blood lipids and lipoproteins.

    https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.035225#d3646671e1

    Or from another review looking at larger changes

    Nevertheless, several RCTs have examined the effect of vegetarian diets on intermediate risk factors of cardiovascular diseases (Table 1). In a meta-analysis of RCTs, Wang et al. (22) found vegetarian diets to significantly lower blood concentrations of total, LDL, HDL, and non-HDL cholesterol relative to a range of omnivorous control diets. Other meta-analyses have found vegetarian diets to lower blood pressure, enhance weight loss, and improve glycemic control to greater extent than omnivorous comparison diets (23-25). Taken together, the beneficial effects of such diets on established proximal determinants of cardiovascular diseases found in RCTs, and their inverse associations with hard cardiovascular endpoints found in prospective cohort studies provide strong support for the adoption of healthful plant-based diets for cardiovascular disease prevention

    https://www.sciencedirect.com/science/article/am/pii/S1050173818300240



  • Yes, this new study has limitations. The authors do note that and aren’t pretending otherwise. This is coming in the context of other studies with similar conclusions which the original article talks about. This new study is a singular imperfect data point, but is combined with other data points that point in the same direction.

    What it is primarily helpful for is in that it has a large N value of 79,468 participants and the population they are looking at doesn’t partake in as many carcinogens that make it harder to tell cancer rates apart (which is both a strength and also a study limitation too)

    From the study

    This study has several other strengths. 1) This is probably the single cancer cohort with the largest number of vegetarians, and especially vegans, who have rarely been studied effectively for cancer incidence. This allows consistent definitions and methods to be applied across all variables; 2) in many studies of vegetarians, vegetarian diets may be relatively transient for some subjects, but less so in AHS-2; 3) the level of validation available for the main variables on which the assignment to vegetarian diets is based; 4) the relatively large Black subgroup in which vegetarian diets have rarely been studied. Race is always a co-variate in our statistical models; and 5) the absence (practically) of cigarette smoking, a common confounder for many cancers, and very little alcohol

    There are also study limitations, the most prominent of which is still the relatively small numbers of less common cancers, particularly among the less common dietary patterns (vegans and pesco-vegetarians) that diminish statistical power; second, there is the relatively health-conscious low-meat-consuming reference group, the Adventist nonvegetarians, that also limits power; third, that we were able to measure dietary and other data only at study baseline and not during follow-up. Finally, there are the limitations of all observational studies, particularly the possibility of unmeasured confounding, which can be limited but never avoided




  • Humans and human ancestors have also been consuming large quantities of plants for far earlier than that. Here’s another paper looking 780,000 years ago finding a wide amount of plants consumed

    we demonstrate that a wide variety of plants were processed by Middle Pleistocene hominins at the site of Gesher Benot Ya’aqov in Israel (33° 00’ 30” N, 35° 37’ 30” E), at least 780,000 y ago. These results further indicate the advanced cognitive abilities of our early ancestors, including their ability to collect plants from varying distances and from a wide range of habitats and to mechanically process them using percussive tools.

    https://www.pnas.org/doi/10.1073/pnas.2418661121

    I am not saying that hunting didn’t happen (it definitely did). I am just saying that more recent research is painting a very different picture of the level of consumption of it






  • usernamesAreTricky@lemmy.mlto196@lemmy.blahaj.zonerule
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    4 个月前

    That is ignoring the vast majority of usage. Read about what professors, teachers, etc. are saying about its use and you will not hear it being used as tool as the major use. Everyone claims they are using it as a tool, but most people are using them to outsource thinking, unfortunately. Which is highly problematic when the outputs of LLMs are highly wrong much of the time. You need to use the same skills to evaluate the output that people are outsourcing away. Tools like calculators at least do their tasks correctly as long as your inputs are correct. The same is not true of LLMs. Moreover, people are blindly trusting the LLMs to a point where they are completely stuck whenever the LLM can’t do something or are wrong

    Tools like calculators do not take away your ability to think logically, just to do route computation. Research is still emerging, but suggests long term negative effects on cognitive abilities from high LLM use

    Also: Regardless of if this graph is caused by schools getting out or not, it’s still very highly used in schools.


  • Honey production is not exactly exploitation free. For instance, queen bees often have their wings clipped or are intentionally killed to be replaced by another

    Moreover, honey production also out competes native/wild bee populations which hurts them. Especially since honeybees are heavily used well outside their native ranges

    We found compelling evidence that honey bee introductions indirectly decrease pollination by reducing nectar and pollen availability and competitively excluding visits from more effective native bees. In contrast, the direct impact of honey bee visits on pollination was negligible, and, if anything, negative. Honey bees were ineffective pollinators, and increasing visit quantity could not compensate for inferior visit quality

    https://esajournals.onlinelibrary.wiley.com/doi/full/10.1002/ecy.3939



  • The US government uses taxes to buy up dairy and meat that was not purchased based on demand, nullifying individual vegan boycotts and artificially propping up those industries.

    That’s taking a really short term view of it. As demand has stayed low enough for long enough, they have cut back on the amount and paid dairy farmers to not operate. These kinds of programs can only prop something up for so long

    but instead has found the greatest successes from lobbying governments to pass animal welfare laws and organizing protests to generate pressure and support for those laws

    Animal welfare laws do not fix the fundamental issue with these systems. As long as the industry exists in a large scale capacity, it will find the cruelest ways to operate. As long as meat, dairy, etc. are consumed in mass, factory farming will exist

    For instance, US beef consumption cannot be supplied by a pasture-based system. There is only enough land to support 27% of the consumption, and that still raises methane emissions by 8% so we would need to be consuming even less if we wanted to avoid emission reductions from a move like that

    Various laws and larger action can be effective though. Like putting plant-based options by default has been tested in some places, has substantially reduced demand and still kept satisfaction high. Or things like prohibiting the production of Fur, Foie Gras, etc.


  • Maybe the EU will pass some legislation that will carry over to the US

    GDPR requires the right to have your data deleted at least, but a lot of companies will only allow that if you are within the EU (because of profit and spite, I suppose). Though some just allowed it for everyone instead

    Similar for California Consumer Privacy Act where a lot of companies will only let you do the stuff it requires if you are within California

    Sort of like the “unsubscribe” button you get at the bottom of some emails. Did they have to pass a law to get that enacted?

    Yes, see the CAN-SPAM Act of 2003