You said:
Sometimes the software does not reflect the hardware.
If gender is the software and the body is the hardware, this is kind of the “born in the wrong body”-stuff many people still use and it implies that there is a kind of hardware/software combination that fits together and a kind of combination that does not.
My guess would be that the left ones are old and difficult to read books professors like precisely because of that, and the right are books which explain things in a more understandable way. But that’s just a guess based on that that’s exactly how I, as a former physics major, would use this meme for physics books.