• 6 Posts
  • 153 Comments
Joined 3 years ago
Cake day: July 1st, 2023
  • NoSpotOfGround@lemmy.worldtoHacker News@lemmy.bestiver.se•The Big Vitamin D Mistake [pdf]English
    3·
    1 month ago

    Abstract:

    Since 2006, type 1 diabetes in Finland has plateaued and then decreased after the authorities’ decision to fortify dietary milk products with cholecalciferol. The role of vitamin D in innate and adaptive immunity is critical. A statistical error in the estimation of the recom- mended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medi- cine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values ≥50 nmol/L. Another study confirmed that 6201 IU/d was needed to achieve 75 nmol/L and 9122 IU/d was needed to reach 100 nmol/L. The largest meta-analysis ever conduct- ed of studies published between 1966 and 2013 showed that 25-hydroxyvitamin D levels <75 nmol/L may be too low for safety and associated with higher all-cause mortality, demolishing the previously presumed U-shape curve of mortality associated with vitamin D levels. Since all-disease mortality is reduced to 1.0 with serum vitamin D levels ≥100 nmol/L, we call public health authorities to consider designating as the RDA at least three-fourths of the levels proposed by the Endocrine Society Expert Committee as safe up- per tolerable daily intake doses. This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereaf- ter. Actions are urgently needed to protect the global population from vitamin D deficiency.

  • NoSpotOfGround@lemmy.worldtoAsk Lemmy@lemmy.world•times you've been called out that stuck with you?
    2·
    10 months ago

    I had a similar thing with a pen, the very same year I think… I had a mildly special pen which one day I lost. Went looking for it and found it sitting on a (slightly older) classmate’s desk, so i grabbed it and said “hey, that’s mine”. He tried to pretend that no, it was his, and he sounded very convincing about it, and even got the teacher involved. They both looked at me with infuriatingly condescending expressions as I explained how it was mine.

    The teacher suggested “just let him have it” to the classmate, who conceded.

    I went back to my desk fuming and scratched my initials into it before returning to show them, "look, see, it was mine! The classmate immediately pointed out “you scratched those in just now” and I think I mumbled something incoherent before going back to my desk, to the teacher’s mortification with the whole situation.

    It had already begun dawning on me at this point that the classmate was right… That wasn’t my pen. It was his and just looked like mine. But it was too late at this point and I didn’t know how to handle it other than to keep quiet and try to forget about it.