Yeah, they’re selling this as a sustainable reaction because the second product is apparently formic acid instead of CO₂. But of course that means less hydrogen per molecule of methanol and the efficiency using sunlight also seems to be low. So I would agree, sustainable in theory but absolutely nowhere near practical for anything.

When you are talking about large molecules like biologics (antibodies, most vaccines, etc.), there are a whole bunch of other things that can go wrong, but not this.

For protein based drugs there are prions: misfolded protein isoforms able to catalytically convert correctly folded proteins, basically following the same logic as the examples of smaller molecules. So far I guess we only know of one group of proteins that do this (like the mad cow disease one) but theoretically it could always happen to others we just don’t know about yet. :)

Sorry if that made anyone feel worse again…

It is tin pest, an autocatalytic transformation of tin, and it is absolutely in the video and related to the topic (see Lvxferres comment). Just to calm down everyone who wants to get angry about clickbait before having watched the video.

Private equity still generally sucks tho.

I personally think so. It is in many ways similar to 5e but a bit denser on rules. It feels like the designers really wanted to make sure that there were no weird corner cases. And while there is a lot of them, the rules all seem very logical and consistent. So when playing it feels a bit more “mechanical” or “game-y” but also less wonky than 5e can be. It is a somwhat different experience than 5e and the rules are available for free at Archive of Nethys. But if you should pick it up really depends on whether your group is unsatisfied with DnD or itching for something new. Our group changed over after trying a one shot and because our DM was getting a bit bored with 5e.

Yeah, just a case of sausage fingers.