I disagree with the ‘massive’ exposure ‘needed’ to observe these effects exaggeration. First, the point of the study was to show it can be carcinogenic, not to parse at exactly what level in humans. Second, effects are seen at the 400ppm level which equates to 20mg/kg. This is 1600mg/day or 8 cans of Diet Coke (@200mg/can) for an 80kg male. That is NOT an impossible level of daily consumption for many.
I suspect further research was done to confirm your linked studies and refine exactly at what minimum levels of daily consumption elicit carcinogenic effects. That will likely be in the full report once released. Until then, you sound like you don’t want it to be true, rather than an impartial evaluator of the research.
the point of the study was to show it can be carcinogenic
Almost anything can be carcinogenic with a high enough exposure. You can pump a rat full of water until it dies and declare that water kills people. But, that doesn’t prove anything or serve a point.
Second, effects are seen at the 400ppm level which equates to 20mg/kg. This is 1600mg/day or 8 cans of Diet Coke (@200mg/can) for an 80kg male. That is NOT an impossible level of daily consumption for many.
In rats! You can’t just multiple a rat study by body weight and expect it to always correlate. That’s why studies are done in larger animals, and sometimes the concept just dies there.
A single study is a statistic. Until they duplicate the results multiple times, and upgrade to monkeys, pigs, or (in a safe way) humans, this is all just noise.
Almost anything can be carcinogenic with a high enough exposure. You can pump a rat full of water until it dies and declare that water kills people.
It would lead to death, but not to cancer. Not everything is carcinogenic, even with high exposure. Causing death by a method other than cancer doesn’t make it carcinogenic.
I disagree with the ‘massive’ exposure ‘needed’ to observe these effects exaggeration. First, the point of the study was to show it can be carcinogenic, not to parse at exactly what level in humans. Second, effects are seen at the 400ppm level which equates to 20mg/kg. This is 1600mg/day or 8 cans of Diet Coke (@200mg/can) for an 80kg male. That is NOT an impossible level of daily consumption for many.
I suspect further research was done to confirm your linked studies and refine exactly at what minimum levels of daily consumption elicit carcinogenic effects. That will likely be in the full report once released. Until then, you sound like you don’t want it to be true, rather than an impartial evaluator of the research.
Almost anything can be carcinogenic with a high enough exposure. You can pump a rat full of water until it dies and declare that water kills people. But, that doesn’t prove anything or serve a point.
In rats! You can’t just multiple a rat study by body weight and expect it to always correlate. That’s why studies are done in larger animals, and sometimes the concept just dies there.
A single study is a statistic. Until they duplicate the results multiple times, and upgrade to monkeys, pigs, or (in a safe way) humans, this is all just noise.
It would lead to death, but not to cancer. Not everything is carcinogenic, even with high exposure. Causing death by a method other than cancer doesn’t make it carcinogenic.
Apple seeds can kill you in large enough quantities
Found the cigarette smoker