Update 1/16 - Adblock has informed BleepingComputer that its engineers fixed the problem and released ABP 3.22.1 and AB 5.17.1 on the Opera and Edge extension stores. The same versions are currently in review on the Mozilla and Chrome add-on stores, and should be made available soon.
It does still work, but YouTube is often pushing breaking changes multiple times per week. It’s really an arms race.