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Joined 3 years ago
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Cake day: June 27th, 2023

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  • Sorry, I meant she should have been Bernie-style grandstanding about it and hammering it home and making it a core part of her campaign more than it not being in her plans at all. I feel like she started with that kind of message and was doing well and ended with the Cheneys like me and ill put a Republican in my cabinet and lost



  • niucllos@lemm.eetoLefty Memes@lemmy.dbzer0.comWhat year is it?
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    2 years ago

    One example does not a rule make, and in the US electoral system money (and the party affiliations that bring it) speaks loudest of all. Maybe going further left wouldn’t work, but going further right certainly hasn’t. When Harris first emerged as the candidate she had such a swell of support, as she moved further right she lost it.


  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    2 years ago

    Sure, there will be examples of problems in any field that has hundreds of thousands to millions of humans working in it. That doesn’t mean there’s a broad crisis, and it doesn’t mean that most research is faked or fallible. In your 2004 example, all of the data wasn’t faked, some images for publication were doctored. There’s been potential links between alzheimer’s and aBeta amyloids since at least 1991 (1), long before this paper that posited a specific aB variant as a causal target. Additionally, other Alzheimer’s causes and treatments are also under investigation, including gut microbiome studies since at leasg 2017 (2). Finally, drugs targeting aB proteins to remove brain plaques work in preclinical trials, indicating that the 2004 paper was at least on the right track even if they cheated to get their paper published. This showcases science working well: bad-faith actors behaved unethically, but the core parts of their work were replicated and found to be effective, so some groups followed that to clinical trials which are still ongoing, and others followed other leads for a more holistic understanding of the disease.

    Also, I’d very much argue that human neurological diseases are both bleeding edge and niche, which inherently means that recognizing problems in studies will take more time than something that is cheaper or faster to test and validate, but problems will eventually be recognized as this one was.

    1. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci USA. 1991;88:7552–6.
    2. Cattaneo, A. et al. Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. Neurobiol. Aging 49, 60–68 (2017).

  • niucllos@lemm.eetoScience Memes@mander.xyz...
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    2 years ago

    I wouldn’t call it a broad crisis, and it isn’t universal. More theoretical sciences or social sciences are more prone to it because the experiments are more expensive and you can’t really control the environment the way you can with e.g. mice or specific chemicals. But most biology, chemistry, etc that isn’t bleeding edge or incredibly niche will be validated dozens to hundreds of times as people build on the work and true retractions are rare



  • I’m not saying me driving an EV does statistically anything to reduce carbon emissions, or even that if I got all my friends and family to go vegan and bike instead of drive cars that it would. I am saying that the broad public doesn’t care about these issues enough to consume differently or vote for policy or politicians that make their lives less convenient in order to fight climate change, and that instead our individual actions to avert climate change contribute to a public ethos that can accept lifestyle changes and that may potentially hold the mega polluting corporations to account and fix our throw-away durable goods culture in a way that media-demonized protests and pestering bought-and-paid politicians never can.


  • While this is basically true, what it ignores is the impact personal decisions make on the ethos around us to build support for legal pressure. I have family that doesn’t disbelieve climate change but isn’t motivated by it, and by us going mostly meatless and buying and EV they’ve started meatless Mondays and Thursdays and are considering an EV for their next car. Our individual actions ripple out, and create a public normalization for these types of changes so that it isnt an uphill battle to get uninformed laypeople to care about climate policy at the polling stations



  • It looks like you’re planning on using windows, in which case I would strongly caution against only 8 GB ram. I have a 4 year old windows laptop with 8 GB RAM, and unless you do a lot to optimize things/kill processes it quickly becomes slow to a very frustrating point. The last thing you want is to open a new tab to look up something the professor said while running a note taking app and have the whole thing freeze for a few minutes and not be able to take notes. RAM is relatively cheap, so I would bit the bullet and either get 16 GB or run Linux.